* Testosterone-Propionate is optimal but Testosterone-Cypionate or Testosterone-Enanthate can be used if the Propionate is a problem for you.
* Trenbolone-Acetate will really set this cycle off more so than any steroid in the stack. If you respond poorly to the hormone you might replace it with Masteron-Propionate at a dosing of 300mg per week; three injections of 100mg each.
* While Equipoise on its own is not a great mass builder, coupled with Testosterone-Propionate and the initial Dianabol use you will produce some very solid gains and see your strength increase very nicely. Further, EQ will promote a more conditioned look while you’re still growing.
* Arimidex may not be needed for some but most will be best served with this low dose. If aromatase related side-effects become a problem you will need to increase the dose to 1mg/eod and in most all men this will eliminate the problems.
* How much weight can you gain from this cycle? That’s a hard question to answer; it will greatly depend on how high your calorie intake is. If you are eating a maintenance level diet you may be able to put on 7-10lbs of tissue, this is excluding any water weight that might come with the Dianabol but any water weight will dissipate shortly after it’s discontinued. Further, the Arimidex will greatly help control this issue. Moreover, the higher your carb intake is above necessity the more water you’ll probably hold.
Recently, a specific peptide inhibitor for ATGL was isolated from white blood cells, specifically mononuclear cells. This peptide was originally identifed as being involved in the regulation of the G 0 to G 1 transition of the cell cycle . This peptide was, therefore, called G0G1 switch protein 2 (encoded by the G0S2 gene). The protein is found in numerous tissues, with highest concentrations in adipose tissue and liver. In adipose tissue G0S2 expression is very low during fasting but increases after feeding. Conversely, fasting or PPARα -agonists increase hepatic G0S2 expression. The protein has been shown to localize to LDs, cytoplasm, ER, and mitochondria. These different subcellular localizations likely relate to multiple functions for G0S2 in regulating lipolysis, the cell cycle , and, possibly, apoptosis via its ability to interact with the mitochondrial antiapoptotic factor Bcl-2. With respect to ATGL regulation, the binding of the enzyme to LDs and subsequent is dependent on a physical interaction between the N-terminal region of G0S2 and the patatin domain of ATGL.
Testosterone can be administered parenterally , but it has more irregular prolonged absorption time and greater activity in muscle in enanthate , undecanoate , or cypionate ester form. These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters, but medical injections are normally done anywhere between semi-weekly to once every 12 weeks. A more frequent schedule may be desirable in order to maintain a more constant level of hormone in the system.  Injectable steroids are typically administered into the muscle, not into the vein, to avoid sudden changes in the amount of the drug in the bloodstream. In addition, because estered testosterone is dissolved in oil, intravenous injection has the potential to cause a dangerous embolism (clot) in the bloodstream.